DIRECTOR OF THE CENTRE
Antonino Zichichi

DIRECTOR OF THE SCHOOL
Michele Pavone-Macaluso

DIRECTORS OF THE COURSE
Lennart Andersson, Stockholm - Sweden
Michele Pavone – Macaluso, Palermo - Italy
Fritz H. Schröder, Rotterdam - The Netherlands
Philip H. Smith, Leeds - United Kingdom

SCIENTIFIC SECRETARIAT
Carlo Pavone, Palermo - Italy
Vincenzo Serretta, Palermo - Italy
Dept. of Urology, University Policlinic Hospital
Via del Vespro 129 – 90127 Palermo
michpav@tin.it   carpavon@tin.it   vserretta@libero.it

ORGANISING SECRETARIAT
E.DI.PO. s.r.l. – Serenella La Cavera
Via Libertà 103, 90143 Palermo
Tel. ++39091343120 / ++39091340255 Fax. ++39091340440
edi.po@tiscalinet.it   slacavera@libero.it   info@edipocongressi.it

The Course will be held under the auspices of the Société Internationale d’Urologie (President: Michael J. Rochford MD, Sidney, Australia; Secretary General: Mostafa Elhilali MD, Montreal, Canada)

SPEAKERS AND CHAIRMEN

Lennart Andersson, Stockholm - Sweden

Laurent Boccon Gibod, Paris   - France

Liliane Boccon Gibod, Paris - France

Aldo V. Bono, Varese - Italy           

Charles B. Brendler, Chicago   - USA       

Giorgio Carmignani, Genova   - Italy         

Gaetano Ciancio, Miami - USA

Mohamed A. Ghoneim, Mansoura - Egypt

Ziya Kirkali, Izmir – Turkey

Tullio Lotti, Napoli – Italy

Gaetano Marino, Torino - Italy     

Luis Martinez-Piñeiro, Madrid - Spain

Giuseppe Martorana, Bologna – Italy

Darwin Melloni, Messina - Italy   

Gregor Mikuz, Innsbruck - Austria     

Rodolfo Montironi, Ancona - Italy     

Don W.W. Newling, Macclesfield - United Kingdom   

Vito Pansadoro, Roma – Italy

Carlo Pavone, Palermo – Italy

Michele Pavone-Macaluso, Palermo – Italy

Francesco Rocco, Milano - Italy

Michael J. Rochford, Sidney - Australia

Peter T. Scardino, New York - USA   

Fritz H. Schroeder, Rotterdam – The Netherlands

Martin Schumacher, Bern - Switzerland   

Cesare Selli, Pisa – Italy

Vincenzo Serretta, Palermo - Italy

Gigliola Sica, Roma – Italy

Philip H. Smith, Leeds – United Kingdom

Mark S. Soloway, Miami – USA   

Gary Steinberg, Chicago - USA

Cora N. Sternberg, Roma - Italy
Hein Van Poppel, Leuven - Belgium
Fred Witjes, Nijmegen - The Nederlands

GENERAL OUTLINE OF THE PROGRAMME

Tuesday 18 May 2004

Arrival

Welcome party

Wednesday 19 May 2004

INTRODUCTORY LECTURES   

PROSTATE CANCER

Thursday 20 May 2004

PROSTATE CANCER

Friday 21 May 2004

SUPERFICIAL BLADDER CANCER

Excursion             

Saturday 22 May 2004

INVASIVE BLADDER CANCER

RENAL CANCER

Sunday 23 May 2004

Departure

Accreditation for Continuing Medical Education (CME) will be granted by the European Board of Urology (EBU), up to a maximum of 18 Credits (1 Credit per hour) in category II.

Accreditation of 19 Credits will be granted by the Italian Ministry of Health (ECM: Educazione Continua in Medicina).

SCIENTIFIC SESSIONS

Wednesday, 19 May 2004

Opening of the Course

08.15 – 08.30   M. J. Rochford, President of the Societé Internationale d'Urologie

Introductory lectures

Session 1

Chairmen: M. Pavone-Macaluso, M.J. Rochford, F.H. Schröder   

08.30   - 08.50     

L. Andersson           

The activities of the WHO collaborating center of genitourinary cancer

08.50   - 09.10     

Z. Kirkali

The activities of the EORTC Urological Group

09.10 - 09.30     

Liliane Boccon Gibod                       

The activities of the Uro-Pathology Group

Prostate cancer

Session 2

Chairmen: A.V. Bono, C.B. Brendler, P.H. Smith

09.30 - 09.50     
Liliane Boccon Gibod: Advances in Pathology
09.50 - 10.00     
Discussion

10.00  - 10.20
G. Sica: Direct effects of a GnRH analogue in prostatic cancer cells
10.20   - 10.30     
Discussion

10.30 - 10.50  
G.Sica:N-cadherin and c-met expression is reduced by recombinant beta interferon in PC-3 cells
10.50 - 11.00   
Discussion

11.00 - 11.30    Coffee-break

Session 3
Chairmen: Liliane Boccon Gibod, F. H. Schröder, G. Sica

11.30 - 11.50   
A. V. Bono: The role of neuro–endocrine cells
11.50 - 12.00     
Discussion

12.00 – 12.20
F. H. Schröder: To screen or not to screen?
The information resulting from the European screening programme

12.20 - 12.30     
Discussion

12.30 – 12.50   
C. B. Brendler: Epidemiology, dietary fat, serum fatty acids and prostate cancer in Jamaica

12.50 – 13.00   
Discussion

13.00    Lunch time

Session 4

Chairmen: G. Carmignani, D.W.W. Newling, V. Pansadoro

15.00 - 15.10
L. Martinez-Piñeiro: Positive margins with laparoscopic prostatectomy

15.10 - 15.20
C. B. Brendler:
Robotic laparoscopic radical prostatectomy: preliminary experience

15.20 – 15.30
Open discussion

15.30 - 15.50  
L. Boccon Gibod: Will laparoscopic surgery replace open radical prostatectomy?

15.50 - 16.00
Discussant : V. Pansadoro

16.00 - 16.20
C. B. Brendler:The 5 mm limit to discriminate between “good” and “bad” prostatic cancer. On what an evidence is it based?
16.20 – 16.30
Discussion

16.30 – 16.50
L. Martinez-Piñeiro: Does it apply to the European situation?
16.50 – 17.00 Discussion

17.00 – 17.30
Coffee break

Session 5
Chairmen: L. Boccon Gibod, V. Pansadoro, V. Serretta

17.30 – 18.15
P. T. Scardino: The New York experience
18.15 – 18.25
Discussion

18.25 – 18.45
C. B. Brendler: Recent advances in the surgical technique

18.45 - 19.05
M. S. Soloway: Surgery, the Miami experience

19.05 - 19.25
G. Carmignani: Bladder neck preservation, is it useful?

19.25 - 19.35
Discussant: M. Soloway

19.35 - 19.45
Open discussion

Thursday 20 May 2004

Prostate cancer

Session 6

Chairmen: D. Melloni, F. Rocco, F.H. Schröder

08.30 – 08.40     

L. Martinez-Piñeiro: How to preserve the nerves with the combined retrograde and descending laparoscopic technique (video)

08.40 - 08.50     
Discussion

08.50 - 09.10     

M. Schumacher: The role of lymphadenectomy

09.10 - 09.20     
Discussion

09.20 - 09.40   

F. H. Schröder: Treatment of the primary tumour in presence of lymph node metastases. Is it useful or necessary?

09.40 – 09.50    

Discussion

09.50 - 10.10     

P.T. Scardino: Nerve sparing and sural nerve implantation; to what an extent can they maintain potency?

10.10 - 10.20     

Discussion

10.20 – 10.50      Coffee-break

Session 7

Chairmen: T. Lotti, L. Martinez Pineiro, M. Pavone-Macaluso

10.50 - 11.10   

G. Carmignani: Does early postoperative treatment with alprostadil or sildenafil (or its derivatives) help to maintain potency?

11.10 - 11.20   

Discussion

11.20 - 11.40     

D. W. W. Newling: Adjuvant hormonal therapy

11.40 - 11.50

Discussion

11.50 - 12.10

L. Andersson: Is watchful waiting still an option?

12.10 - 12.20

Discussion

12.20 - 12.40

F. Witjes: Treatment of advanced disease

12.40 - 12.50

Discussion

13.00        Lunch time

Session 8

Chairmen: M. S. Soloway, C.N. Sternberg, F. Witjes

15.00 - 15.20

D. W. W. Newling: New modalities of androgen deprivation antiandrogen monotherapy, intermittent administration, LHRH antagonists

15.20 - 15.30   

Discussion

15.30 – 16.00   

P. T. Scardino: Indication and results of hormonal treatment before surgery and upon biochemical relapse after radical prostatectomy

16.00 - 16.20   

C. N. Sternberg: Treatment of hormone resistant cancer

16.20 - 16.30     

Discussion

16.30 – 17.00      Coffee-break

Session 9

Chairmen: L. Andersson, C. Pavone, M. Schumacher

17.00 - 17.20     

P. T. Scardino: Prevention of prostate cancer

17.20   - 17.30   

Discussion

17.30 - 17.50   

P. H. Smith: Conclusions

17.50 - 19.00     

M. S. Soloway: Discussion of cases

Friday, 21 May 2004

Bladder cancer

Session 10

Chairmen: M. A. Ghoneim, R. Montironi, G. Steinberg

08.30 - 08.50     

R. Montironi: Advances in Pathology   

08.50 - 09.00     

Discussion

Superficial

09.00 - 09.20   

M. S. Soloway: New concepts on treatment of superficial bladder cancer (low risk versus high risk)

09.20 - 09.30     

Discussion

09.30 - 09.50     

A. V. Bono: Indications for multiple random biopsies

09.50 - 10.00     

Discussion

10.00 - 10.20   

Z. Kirkali: Does intravesical treatment influence progression?

10.20 - 10.30     

Discussion

10.30 - 10.50   

V. Serretta: Does hyperthermia improve the results of intravesical chemotherapy?

10.50 - 11.00     

Discussion

11.00 - 11.20   

G. Steinberg: Surveillance and detection of superficial bladder cancer. When should we proceed to cystectomy?

11.20 - 11.30       

Discussion

11.30 - 11.45     coffee time

Saturday, 22 May 2004

Bladder cancer

Session 11

Chairmen: G. Marino, G. Martorana, P.H. Smith

Invasive

8.30 - 8.50     

C. N. Sternberg: Is there still a role for bladder preservation?

8.50 - 9.00     

Discussion

9.00 - 9.20     

M. A. Ghoneim: Role of lymphadenectomy

9.20 - 9.30     

Discussion

9.30 - 9.40   

Discussant: M. Schumacher

Extended lymphadenectomy in association with cystectomy

9.40 - 10.00   

G. Steinberg: Nerve–sparing radical prostatectomy and orthotopic bladder reconstruction in males and females. Update on technique

10.00 - 10.10     

Discussion

10.10 - 10.40      Coffee break

Session 12

Chairmen: L. Andersson, M. A. Ghoneim, M.S. Soloway

10.40 - 11.00   

M. A. Ghoneim: Evolution of diversion following cystectomy

11.00 - 11.10     

Discussion

11.10 – 11.30     

G. Marino: Ileal T pouch as urinary continent cutaneous diversion

11.30 – 11.50     

C. Pavone: Can we predict response to local or systemic chemotherapy?

11.50 - 13.00     

M. S. Soloway: Discussion of cases

13.00        Lunch time

Renal cancer

Session 13
Chairmen: G. Ciancio, Z. Kirkali, C. Selli

14.30 - 14.50
G. Mikuz: Advances in Pathology
14.50 - 15.00
Discussion

15.00 - 15.20
C. N. Sternberg: Treatment of metastatic disease
15.20 - 15.30
Discussion

15.30 - 15.50
F. Witjes: Advances in immunotherapy

15.50 - 16.00
Discussant: C. Selli

16.00 - 16.40
G. Ciancio: Surgery of large renal masses with caval involvement

16.40 – 17.10 Coffee break

Session 14
Chairmen: M. J. Rochford, P.H. Smith, H. van Poppel

17.10 - 17.30
C. Selli: Conservative versus radical surgery

17.30 - 17.40
Discussant: L. Martinez-Piñeiro

17.40 - 18.00
H. van Poppel: Tumorectomy versus partial nephrectomy

18.00 – 18.20
Z. Kirkali: Lumbar versus anterior (transperitoneal) versus laparo-or lumboscopic approach
18.20 – 18.30
Discussion

18.30 – 18.50
G. Martorana: Role of lymphadenectomy
18.50 – 19.00
Discussion

19.00 - 19.30
Closure of the Course

GENERAL INFORMATION

Please read carefully

Erice is a small town situated on a hilltop at a height 751 m . above sea level, therefore cooler than the surrounding country: we suggest you to take a sweater and a raincoat with you!

Facilities in Erice are limited: a Post Office, a Bank (Banco di Sicilia), a few stores and souvenirs shops.

The Secretariat of the Centre
is located in Erice, San Rocco Institute, Via Guarnotta, 26
Telephone: ++39.0923.869107 – Fax: ++39.0923.869226 –
E.mail: fiorella@ccsem.infn.it .

Last minute local help:
Erice ++39 0923 869107 / ++39 0923 869068;
Palermo ++39 091 343120 / ++39 091 340255;
Prof. Pavone – Macaluso mobile ++39 339 2434555;
Mrs Serenella La Cavera mobile ++39 329 3013891

Lecturers and participants, who have notified in due time date, hour and flight number regarding their arrival, will be picked up at airport ( Palermo or Trapani ) and transferred by private bus or car to Erice. Participants who have failed to provide detailed information about their arrival time may reach Erice by taxi (fare is approximately € 160,00 from Palermo and € 130,00 from Trapani ) and this expense will not be reimbursed.

Upon arrival, all lecturers and participants will have to contact the Secretariat of the Centre (see above address) for the checking-in procedures. At this moment, lecturers and participants will be requested to fill an arrival form and will be informed about the place that the E. Majorana Centre has provided for their accommodation (see next paragraph).Younger participants may be requested to share a twin-bedded room

Lecturers and participants will be housed in one of the ancient monasteries belonging to the Ettore Majorana Foundation and Centre for Scientific Culture: San Domenico, San Francesco, San Rocco (rooms with private bath) or in one of the affiliated hotels.

Guests of hotels will take breakfast at their hotels; guests of monasteries will take breakfast at San Rocco Institute.

Coffee, tea, mineral water, sandwiches and sweet biscuits are available at the lecture hall at San Domenico Institute during the coffee-breaks and at San Rocco Institute all day through. Lunches and dinners will be served at several restaurants connected with the Ettore Majorana Centre. Your signature is kindly requested at the end of your meal.

A social programme will be arranged, as follows:

Tuesday 18 th May
09:30 p.m. - Welcome party after dinner, get together at “ Marsala wine cellar” in San Rocco Institute with all participants

Thursday 20 th May
08:30 p.m. - Social dinner, San Francesco Institute

Friday 21 st May
11:30 a.m. - Excursion: lunch at windmill near the salt-pan and guided visit of Mothia
08:00 p.m. – Concert of Maria Chiara Pavone, San Domenico Institute

Saturday 22d May
08:30 p.m. - Farewell dinner, Ulisse restaurant

Accompanying persons' programme:

Wednesday 19 th May
10:00 a.m. - Guided tour of Erice

Thursday 20 th May
09:00 a.m. - Guided excursion to Monreale (near Palermo ). Lunch at restaurant “ Charleston ” at Mondello beach

Saturday 22d May

09:00 a.m. – Guided excursion to Mazara del Vallo and Selinunte. Lunch en route.

Remember that you can dress informally at all times: no formal dress will ever be required .

Erice is paved with medieval large stone cobbles. They may be slippers when wet. Consider this for your shoes and avoid narrow heels for ladies . Hard shoes are best worn during excursions.